Major topics of research:

• Human genetic resistance to mild and severe malaria
  (Dr. Jennifer Evans, Dr. Christian Timmann et al.)
• Genetic basis for immunosuppression and allergy-type reactions in a human nematode infection
  Dr. Christian Timmann
  
• Genetic diagnosis and clinical definition of Familial Mediterranean Fever
  Dr. Christian Timmann, Sonja Burwinkel
• Genetic basis for immunotolerance and allergy-type reactions in a nematode infection
  (Dr. Christian Timmann)
• Human genetic resistence to tuberculosis
  Prof. Dr. Christian G. Meyer, Dr. Thorsten Thye, Birgit Muntau, Gerd Ruge
• Endothelial receptors for Plasmodium falciparum
  Dr. Daniela Kuhn, Dr. Claudia Esser et al.

Homepage Department of Molecular Medicine

Laboratory Brattig in the Department of Molecular Medicine
PD Dr. rer.nat. Norbert W. Brattig
Bernhard Nocht Institute for Tropical Medicine
Bernhard-Nocht-Str. 74
20359 Hamburg
Germany
Phone +49-(0)40-42818-530
Fax: -400

Major topics of research:

• Identification of parasitism-relevant gene and gene products of parasitic nematodes: Strongyloides immunomodulatory secreted proteins
• Mechanism of malaria-associated anemia

Homepage Laboratory Brattig

Pathology and Körber Laboratory of HIV Research
Prof. Dr. Paul Racz
Phone +49-(0)40-42818-499
Fax: -400

Major topics of research:

• Detecion of viral mRNA expression in lymphatic tissues during HIV and SIV infection
• In situ analysis of host reactions in Leper and schistosomiasis

Homepage Pathology and Körber Laboratory of HIV Research

Research Group May (Infectious Disease Epidemiology)
PD Dr. Jürgen May
Phone +49-(0)40-42818-369
Fax: -512

Major topics of research:

The Research Group Infection Epidemiology has been established at BNI in November 2004. The aim is to link overlapping areas of epidemiology, molecular biology, and infection medicine. Focal points are infection epidemiology and genetic molecular epidemiology of malaria, helminth infections, and other tropical diseases. A superior aim is to join basic science objectives and implementation of control measures in the community. An evaluation of intermittent preventive treatment of infants (IPTi) with Sulfadoxin-Pyrimethamine as a mean of malaria control has started recently. Further randomized clinical trials of treatment and control of malaria and other tropical diseases will follow.

Homepage Laboratory May

Clinical Research
Prof. Dr. Gerd-Dieter Burchard
Tel: +49-(0)40-42818-390/391 Fax: -394

Major topics of research:

• Pathogenesis and significance of cardiac and renal organ manifestations in Plasmodium falciparum infection
• Cardiac and renal organ manifestations in Plasmodium falciparum malaria
• GPI-induced apoptosis in murine cardiomyocytes and inhibition by caspase-inhibitors
• Malaria, Toll-like receptors and GPI
  

Homepage Clinical Research

Kumasi Centre for Cooperative Research in Tropical Medicine (KCCR), Ghana
Dr. Thomas Kruppa
University Post Office KNUST
Kumasi Ghana Phone/Fax: ++233 51 60351
Email: kccr@africaonline.com.gh

Current projects:

• The genetic influence on resistance and susceptibility to malaria
  Principal Investigators: Dr. E.N.L. Brown, Prof. Tsiri Agbenyega, Dr. Jennifer Evans (BNI) & Professor. R. Horstmann (BNI)
• Genetics of congenital hearing impairment
  Principal Investigators: Professor Dr. Dr. G.W. Brobby, Dr. G. K. Amedofu & PD Dr. C. G. Meyer (BNI)
  
• Ecology and Modes of Transmission of Mycobacterium ulcerans
  Principal Investigators: Prof. Ohene Adjei, Dr. Mark Evans and Dr. Thomas Kruppa (BNI)
• Study on antibiotic treatment of tissue nematode infection
  Principal Investigators: Professor Dr. Ohene Adjei & Prof. Dr. Achim Hörauf
• Research on a vaccine against onchocerciasis (riverblindness)
  Principal Investigators: Professor Dr. Ohene Adjei & PD Dr. Achim Hörauf
• Study on elephantiasis (lymphatic filariasis) in the coastal area of South West Ghana
  Principal Investigators: Dr. Sam Dunyo (Noguchi Institute), Professor Dr. Ohene Adjei, Dr. Thomas Kruppa (BNI) & Prof. Dr. Achim Hörauf
  

KCCR Homepage

Last update: 09/2008